Out of control blood sugar fluctuations compromises normal bone modeling and that can increase the risk of fractures. Post-menopausal women with poor glycemic control are at high risk for bone fractures.
Bone mass or bone density are different from bone architecture and functional strength. While many post-menopausal women show to have a normal range of bone mass or density, they do feel some weakening of bone architecture. Researchers believe that poor glycemic control increases AGEs (advanced glycation end products) in the bone, which impacts the collagen network and function of the bone cells. This is based on studies showing:
- Low bone mass (63%) and bone architecture deterioration (73%) are observed in postmenopausal women with T2D
If you are a postmenopausal women with T2D, talk to your doctor about methods of fracture assessment like FRAX or TBS-adjusted FRAX.
